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An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans
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Chapters
- 00:05Title
- 01:09Preparations
- 03:03Performing the Assay
- 05:21Movie Analysis
- 09:10Results from Screening Several Strains/Genotypes
- 10:03Conclusion
C. elegans is a useful model for studying the effects of ethanol on behavior. We present a behavioral assay that quantifies the effects of ethanol on the locomotion speed of crawling worms; both initial sensitivity and the development of acute functional tolerance to ethanol can be measured with this assay.
