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Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination
Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination

Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination

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06:49 min

July 29, 2015

DOI:

06:49 min
July 29, 2015

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Summary

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Focal demyelination is induced in the optic nerve using lysolecithin microinjection. Visual evoked potentials are recorded via skull electrodes implanted over the visual cortex to examine the signal conduction along the visual pathway in vivo. This protocol details the surgical procedures underlying electrode implantation and optic nerve microinjection.

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