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Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice
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Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice

Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice

DOI:
10.3791/53076-v

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06:22 min

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September 17, 2015

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, ,
1Pharmakologisches Institut,Universität Heidelberg

Chapters

  • 00:05Title
  • 01:43Left Anterior Papillary Muscle Isolation, Equilibration and Stimulation
  • 04:02Results: Representative Murine Left Anterior Papillary Muscle Contractility Measurements
  • 05:25Conclusion

Summary

Automatic Translation

Automatic Translation

Murine left ventricular papillary muscle can be used to investigate cardiac contractility in vitro. This article describes in detail the isolation and experimental protocols to study cardiac contractile characteristics.

Tags

Keywords: Papillary MuscleCardiac ContractilityCardiac InotropyMouse HeartOrgan BathTwitch ForceContractile ParametersCalcium-dependent ContractilityFrequency-dependent ContractilityPharmacological AgentsTransgenic Animal ModelsCardiac PhysiologyCardiac Pathophysiology

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