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A Simple Alternative to Stereotactic Injection for Brain Specific Knockdown of miRNA
 

A Simple Alternative to Stereotactic Injection for Brain Specific Knockdown of miRNA

Article doi: 10.3791/53307
December 26th, 2015

Summary December 26th, 2015

MicroRNAs play crucial roles in the brain and are potential targets for modeling neuro-degeneration. However, perturbing miRNA levels is challenging due to the short length of miRNA and inaccessibility of the brain tissue. This video presents a method for antagomir design and brain specific delivery using a neuropeptide in mice.

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