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JoVE Journal
Neuroscience

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Peering at Brain Polysomes with Atomic Force Microscopy
 

Peering at Brain Polysomes with Atomic Force Microscopy

Article DOI: 10.3791/53851
March 16th, 2016

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Summary March 16th, 2016

While ribosome structure has been extensively characterized, the organization of polysomes is still understudied. To overcome this lack of knowledge, we present here a detailed preparation protocol for accurate imaging of mammalian polysomes by atomic force microscopy (AFM) in air and liquid.

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