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Chapters
- 00:05Title
- 00:32Preparation of Tools
- 02:09Embryo Preparation
- 03:59Microinjection of Nephrotoxin Solution
- 06:32Results: Experimental Timeline and Post Injection Edema Assay
- 07:34Conclusion
Renal injuries incurred from nephrotoxins, which include drugs ranging from antibiotics to chemotherapeutics, can result in complex disorders whose pathogenesis remains incompletely understood. This protocol demonstrates how zebrafish can be used for disease modeling of these conditions, which can be applied to the identification of renoprotective measures.
