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JoVE Journal Developmental Biology
In vitro en in vivo modellen voor de studie van het hoornvlies endotheel-mesenchymale transitie
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In vitro en in vivo modellen voor de studie van het hoornvlies endotheel-mesenchymale transitie

Article DOI: 10.3791/54329-v • 09:06 min • August 20th, 2016
August 20th, 2016 •
1,2, 3, 3, 1, 3, 2,4, 3,4
1Department of Ophthalmology, Far Eastern Memorial Hospital, 2Institute of Clinical Medicine, National Taiwan University, 3Department of Ophthalmology, National Taiwan University Hospital, 4College of Medicine, National Taiwan University

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Een primaire kweek van runder corneale endotheelcellen werd gebruikt om het mechanisme van corneale endotheel-mesenchymale overgang te onderzoeken. Verder werd een rat hoornvliesendotheel cryoinjury model gebruikt om corneale endotheel-mesenchymale overgang in vivo te demonstreren.

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Developmental Biology cornea endotheel mesenchymale transitie matrix metalloproteïnase β-catenine N-cadherine intracamerale injectie
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