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The Arteriovenous (AV) Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering
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1Department of Plastic and Hand Surgery and Laboratory for Tissue Engineering and Regenerative Medicine,University Hospital of Erlangen, Friedrich-Alexander University of Erlangen-Nürnberg (FAU), 2Genetic Engineering and Biotechnology Institute for Postgraduate Studies,Baghdad University, 3Department of Plastic, Hand and Microsurgery,Sana Klinikum Hof GmbH
Chapters
- 00:05Title
- 01:33Preparing the Rat for Surgery
- 02:37The Arteriovenous Loop Model Surgery
- 06:59Results: Micro Computer Tomography (Micro CT) and Staining after 6 Weeks of AV Loop Implantation
- 07:46Conclusion
We describe a microsurgical approach for the generation of an arteriovenous (AV) loop as a model for analyzing vascularization in vivo in an isolated and well-characterized environment. This model is not only useful for the investigation of angiogenesis, but is also optimally suited for engineering axially vascularized and transplantable tissues.
