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Genetics

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Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans
 

Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans

Article doi: 10.3791/54810
November 14th, 2016

Summary November 14th, 2016

Genetically-encoded histone-miniSOG induces genome-wide heritable mutations in a blue light-dependent manner. This mutagenesis method is simple, fast, free of toxic chemicals, and well-suited for forward genetic screening and transgene integration.

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