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Bioengineering
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Scaffold-supported Transplantation of Islets in the Epididymal Fat Pad of Diabetic Mice
 

Scaffold-supported Transplantation of Islets in the Epididymal Fat Pad of Diabetic Mice

Article doi: 10.3791/54995
July 23rd, 2017

Summary July 23rd, 2017

This protocol demonstrates murine islet isolation and seeding onto a decellularized scaffold. Scaffold-supported islets were transplanted into the epididymal fat pad of streptozotocin (STZ)-induced diabetic mice. Islets survived at the transplantation site and reversed the hyperglycemic condition.

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