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JoVE Journal
Immunology and Infection

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A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment
 

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

Article DOI: 10.3791/55383
May 25th, 2017

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Summary May 25th, 2017

Antibiotic efficacy is most commonly determined by conducting killing kinetic studies and measuring colony forming units (CFUs). By integrating scanning electron microscopy (SEM) with these standard methods, we can distinguish the pharmacological effects of treatment between different antibiotics.

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