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Journal / Genetics / Enda molekyl Analys av Laser Lokaliserade…
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Genetics

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JoVE Journal Genetics
Enda molekyl Analys av Laser Lokaliserade psoralen Addukter
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Enda molekyl Analys av Laser Lokaliserade psoralen Addukter

Article DOI: 10.3791/55541-v • 11:46 min • April 20th, 2017
April 20th, 2017 •
1, 1, 1, 1, 1, 1, 1
1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health

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Lasrar används ofta i studier av cellulärt svar på DNA-skada. Emellertid, de genererar lesioner vars avstånd, frekvens, och kollisioner med replikationsgafflar sällan känne. Här beskriver vi en metod som gör det möjligt att bestämma dessa parametrar med laser lokaliserad interstrand tvärbindningar.

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Genetik DNA-skada laser lokalisering DNA-fiber interstrand tvär enda molekyl avbildning
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