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Modeling Fast-scan Cyclic Voltammetry Data from Electrically Stimulated Dopamine Neurotransmission Data Using QNsim1.0
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1Center for Neuroscience,University of Pittsburgh, 2Department of Physical Medicine & Rehabilitation,University of Pittsburgh, School of Medicine, 3Safar Center for Resuscitation Research,University of Pittsburgh, 4Department of Biological Sciences, Mellon College of Science,Carnegie Mellon University
Chapters
- 00:05Title
- 00:41Launching QNsim1.0 and Initialization of the Simulation Environment
- 03:01Using the Simulator Window
- 06:19Results: Simulations of Sample Data
- 07:04Conclusion
Fast-scan cyclic voltammetry can monitor in vivo dopamine neurotransmission in the context of drugs, disease, and other experimental manipulations. This work describes the implementation of QNsim1.0, a software to model electrically stimulated dopamine responses according to the quantitative neurobiological model to quantify estimates of dopamine release and reuptake dynamics.
