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Neurobehavioral Assessments in a Mouse Model of Neonatal Hypoxic-ischemic Brain Injury
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1Department and Research Institute of Rehabilitation Medicine,Yonsei University College of Medicine, 2Brain Korea 21 PLUS Project for Medical Science,Yonsei University, 3Department of Rehabilitation Medicine,Yonsei University Wonju College of Medicine, 4Rehabilitation Institute of Neuromuscular Disease,Yonsei University College of Medicine, 5Graduate Program of NanoScience and Technology,Yonsei University
Chapters
- 00:05Title
- 01:06Mouse Model of Neonatal HI Brain Injury
- 02:47Passive Avoidance Task
- 03:46Ladder Walking Test
- 05:07Grip Strength Test
- 06:21Results: Neonatal Hypoxia-schemia Brain Injured Mice Categorization and Behavioral Assessments
- 07:35Conclusion
We performed unilateral carotid artery occlusion on postnatal day 7-10 CD-1 mouse pups to create a neonatal hypoxic-ischemic (HI) model and investigated the effects of HI brain injury. We studied neurobehavioral functions in these mice compared to non-operated normal mice.
