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JoVE Journal
Cancer Research

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Target Cell Pre-enrichment and Whole Genome Amplification for Single Cell Downstream Characterization
 

Target Cell Pre-enrichment and Whole Genome Amplification for Single Cell Downstream Characterization

Article doi: 10.3791/56394
May 15th, 2018

Summary May 15th, 2018

This protocol is to recover and prepare rare target cells from a mixture with non-target background cells for molecular genetic characterization at the single-cell level. DNA quality is equal to non-treated single cells and allows for single-cell application (both screening based and targeted analysis).

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