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JoVE Journal
Immunology and Infection

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饱和脂肪酸诱导神经酰胺相关巨噬细胞死亡
 
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饱和脂肪酸诱导神经酰胺相关巨噬细胞死亡

Article DOI: 10.3791/56535
October 31st, 2017

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Summary October 31st, 2017

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本文阐述了一种从骨髓细胞中提取小鼠原发巨噬蛋白的方法, 并提出了制备 BSA-脂肪酸共轭物的简便方法。然后我们证明饱和脂肪酸能诱导巨噬细胞死亡, 这种细胞死亡与神经酰胺水平的细胞积累呈正相关。

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