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Synthesis and Mass Spectrometry Analysis of Oligo-peptoids
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JoVE Journal Chemistry
Synthesis and Mass Spectrometry Analysis of Oligo-peptoids

Synthesis and Mass Spectrometry Analysis of Oligo-peptoids

DOI:
10.3791/56652-v

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11:44 min

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February 21, 2018

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, , ,
1Department of Chemistry,University of the Pacific

Chapters

  • 00:04Title
  • 01:00Synthesis of Peptoid
  • 05:54MS Measurements and Sequence Analysis
  • 09:12Results: Mass Spectrometry Analysis of Oligo-peptoid Ac-Nae-(Npe-Nme)4-NH2
  • 10:36Conclusion

Summary

Automatic Translation

Automatic Translation

A protocol is described for the manual synthesis of oligo-peptoids followed by sequence analysis by mass spectrometry.

Tags

Keywords: Oligo-peptoidsPeptoid SynthesisMass SpectrometryTandem Mass SpectrometryRink Amide ResinTMFPiperidineDMFBromoacetylation2-methoxyethylamineSolid-phase SynthesisCharacterizationMonomer Sequence

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