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Cancer Research

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An In Vivo Murine Sciatic Nerve Model of Perineural Invasion
 

An In Vivo Murine Sciatic Nerve Model of Perineural Invasion

Article DOI: 10.3791/56857
April 23rd, 2018

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Summary April 23rd, 2018

We describe an in vivo murine model of perineural invasion by injecting syngeneic pancreatic cancer cells into the sciatic nerve. The model allows for quantification of the extent of nerve invasion, and supports investigation of the cellular and molecular mechanisms of perineural invasion.

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