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JoVE Journal Cancer Research
To effekter av melanom Cell-derived faktorer på benmarg adipocytter differensiering
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To effekter av melanom Cell-derived faktorer på benmarg adipocytter differensiering

Article DOI: 10.3791/57329-v • 07:00 min • August 23rd, 2018
August 23rd, 2018 •
1, 2, 1, 3
1Department of Rheumatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 2Department of Nephrology and Rheumatology, Yongchuan Hospital of Chongqing Medical University, 3Department of Medical Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University

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Her presenterer vi en pålitelig og enkel todimensjonal (2D) coculture system for å studere samspillet mellom kreftceller og benmarg adipocytter, som avslører en dobbel effekt av melanom celle-avledet faktorer på benmarg adipocytter differensiering og utgjør også en klassisk metode for mekanistisk studier av bein metastasering.

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Kreftforskning problemet 138 benmarg adipocyte bein metastasering melanom coculture differensiering membran sett inn
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