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Dubbla effekter av melanom Cell-derived faktorer på benmärgen adipocyter differentiering
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Dubbla effekter av melanom Cell-derived faktorer på benmärgen adipocyter differentiering

Article DOI: 10.3791/57329-v • 07:00 min • August 23rd, 2018
August 23rd, 2018 •
1, 2, 1, 3
1Department of Rheumatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 2Department of Nephrology and Rheumatology, Yongchuan Hospital of Chongqing Medical University, 3Department of Medical Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University

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Här presenterar vi en pålitlig och enkel tvådimensionell (2D) coculture system för att studera interaktionen mellan tumörceller och benmärgen adipocyter, som avslöjar en dubbla melanom cell-derived faktorer påverkar de benmärgen adipocyter differentiering och utgör också en klassisk metod för mekanistiska studier av skelettmetastaser.

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Cancerforskning fråga 138 benmärgen fettceller skelettmetastaser melanom coculture differentiering membran infoga
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