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JoVE Journal
Bioengineering

This content is Open Access.

An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing
 

An Ultrahigh-throughput Microfluidic Platform for Single-cell Genome Sequencing

Article doi: 10.3791/57598
May 23rd, 2018 Usage Statistics

Summary May 23rd, 2018

Single-cell sequencing reveals genotypic heterogeneity in biological systems, but current technologies lack the throughput necessary for the deep profiling of community composition and function. Here, we describe a microfluidic workflow for sequencing >50,000 single-cell genomes from diverse cell populations.

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