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使用大鼠的耳镜可视化和行为拍片启动反应进行验证，对传导性听力损失进行简单手术诱导
JoVE Journal
Neuroscience
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JoVE Journal Neuroscience
Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat
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使用大鼠的耳镜可视化和行为拍片启动反应进行验证，对传导性听力损失进行简单手术诱导

DOI:
10.3791/57993-v

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00:06 min

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October 26, 2019

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, , , , , ,
1Instituto de Neurobiología,Universidad Nacional Autónoma de México, México, 2State Key Laboratory of Marine Pollution (SKLMP),City University of Hong Kong, Hong Kong, 3Department of Biomedical Sciences, College of Veterinary Medicine and Life Sciences,City University of Hong Kong, Hong Kong, 4Department of Physics,City University of Hong Kong, Hong Kong, 5Department of Clinical Oncology,Queen Elizabeth Hospital, Hong Kong, 6Department of Materials Science and Engineering,City University of Hong Kong, Hong Kong

Chapters

  • 00:00Title
  • 01:05Animals
  • 01:36Surgical Setup
  • 02:18Surgical Induction of Conductive Hearing Loss
  • 02:55Otoscope Visualization
  • 03:47Behavioral Assessment
  • 04:38Failure to Induce CHL
  • 05:43Conclusion

Summary

Automatic Translation

Automatic Translation

在这里，我们提出了一个协议，通过手术性鼓膜穿刺建立可复制的传导性听力损失诱导，并通过耳镜可视化和行为评估通过拍拍惊吓进行验证。

Tags

Surgical InductionConductive Hearing LossOtoscope VisualizationBehavioral Clap Startle ResponseRat ModelTympanic Membrane PunctureMalleus RemovalAnesthesiaSurgical ProcedureEthical Approval

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