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A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice
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A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice

DOI:
10.3791/58287-v

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07:00 min

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October 05, 2018

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, , , , , , ,
1Department of Optometry and Vision Sciences,University of Melbourne

Chapters

  • 00:04Title
  • 00:55Intraocular Pressure (IOP) Measurement in Conscious Rats
  • 02:04Induction of Intraocular Pressure Elevation in the Rat
  • 04:03Demonstration of Purse-String Suture on the Mouse
  • 05:08Results: Chronic IOP Elevation via Circumlimbal Suture Induced Functional Deficits in the Inner Retina
  • 06:10Conclusion

Summary

Automatic Translation

Automatic Translation

Chronic ocular hypertension is induced by applying a circumlimbal suture in rats and mice, leading to functional and structural deterioration of the retinal ganglion cells consistent with glaucoma.

Tags

Keywords: GlaucomaIntraocular PressureIOPCircumlimbal SutureRatMouseVisual DemonstrationSuturingRebound TonometryPurse-string SutureEpiscleral VeinsPost-surgical IOP Spike

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