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October 26, 2018
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Summary
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El protocolo aquí descrito permite a los investigadores modificar específicamente cápsida de adenovirus en sitios seleccionados por simple química. Blindado adenovirus vectores partículas pueden generarse vectores de transferencia génica versión y vector host interacciones pueden ser estudiadas.
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Cite this Article
Jönsson, F., Hagedorn, C., Kreppel, F. Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting. J. Vis. Exp. (140), e58480, doi:10.3791/58480 (2018).
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