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JoVE Journal
Neuroscience

This content is Open Access.

Effects of Blast-induced Neurotrauma on Pressurized Rodent Middle Cerebral Arteries
 

Effects of Blast-induced Neurotrauma on Pressurized Rodent Middle Cerebral Arteries

Article doi: 10.3791/58792
April 1st, 2019

Summary April 1st, 2019

Here, we present a protocol to describe methods for ex vivo vascular reactivity determination following a primary blast traumatic brain injury (bTBI) using isolated, pressurized, rodent middle cerebral arterial (MCA) segments. bTBI induction is accomplished using a shock tube, also known as an Advanced Blast Simulator (ABS) device.

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