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Chapters
- 00:04Title
- 00:48Animal Preparation
- 01:49Pulp Exposure
- 03:04Post Procedure Follow-Up and Experiment Termination
- 04:18Micro-Computed Tomography (Micro-CT)
- 05:42Contouring
- 06:54Histology
- 08:27Results: Representative Micro-CT and Histological Analyses
- 09:41Conclusion
Here, we present a protocol to locally induce apical periodontitis in mice. We show how to drill a hole in the mouse's tooth and expose its pulp, in order to cause local inflammation. Analysis methods to investigate the nature of this inflammation, such as micro-CT and histology, are also demonstrated.
