Gold Nanoparticle Modified Carbon Fiber Microelectrodes for Enhanced Neurochemical Detection

The method is significant because it enables neurochemical detection with high spatial and temporal resolution which can potentially enhance in vivo methods of neurochemical detection. The main advantage of this technique is that it is a quick, easy and reproducible method to enhance the sensitivity and temporal resolution of neurotransmitter detection. Demonstrating the procedure will be Sanuja Mohanaraj and Pauline Wonnenberg, graduate students from my laboratory.

To begin, separate carbon fiber material into individual strands and pull a single seven-micrometer diameter carbon fiber from a strand. Connect a vacuum line to a borosilicate glass capillary and aspirate the carbon fiber into the capillary. Then cut a 10-centimeter by 25-centimeter piece of cardboard to serve as an electrode holder.