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Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
JoVE Journal
Behavior
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JoVE Journal Behavior
Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury

DOI:
10.3791/59637-v

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09:16 min

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June 21, 2019

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, , , ,
1Department of Neurosurgery,Jacobs School of Medicine and Biomedical Science, 2Comparative Medicine Laboratory Animal Facilities,University at Buffalo, 3emka Technologies

Chapters

  • 00:04Title
  • 00:51Craniectomy
  • 03:30Lateral Fluid Percussion Injury (FPI)
  • 04:48Implantation of Cortical EEG Electrodes and Video-EEG Recording
  • 06:36Collection of Video-EEG Recordings and Analysis
  • 07:10Results: Lateral Fluid-Percussion Induced Traumatic Brain Injury
  • 08:45Conclusion

Summary

Automatic Translation

Automatic Translation

Here we present a protocol to induce severe TBI with the lateral fluid percussion injury (FPI) model in adult, male Wistar rats. We also demonstrate the use of a wireless telemetry system to collect continuous video-EEG recordings and monitor for epileptiform discharges consistent with post-traumatic epileptogenesis. 

Tags

Keywords: Wireless Video-EEGLateral Fluid-percussionTraumatic Brain InjuryEpileptiform DischargesPost-traumatic EpilepsyRat ModelTelemetryCraniectomyDuraCyanoacrylate GlueDental Cement

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