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JoVE Journal Cancer Research
En human perifert blod mononukleär cell (PBMC) inympad humaniserad xenograft modell för translationell Immuno-onkologi (I-O) forskning
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En human perifert blod mononukleär cell (PBMC) inympad humaniserad xenograft modell för translationell Immuno-onkologi (I-O) forskning

Article DOI: 10.3791/59679-v • 08:17 min • August 15th, 2019
August 15th, 2019 •
*1, *1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1BeiGene (Beijing) Co., Ltd.
* These authors contributed equally

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Vi beskriver en human perifert blod mononukleär cell (PBMC)-baserad humaniserad xenograft musmodell för translationell Immuno-onkologi forskning. Detta protokoll kan fungera som en allmän riktlinje för att fastställa och karakterisera liknande modeller för I-O-behandlingsbedömning.

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Retraktion immunonkologi (I-O) perifert blod mononukleär cell (PBMC) Tislelizumab BGB-A317 immunobristfällig humaniserad cyklofosfamid (CP) patient-derived xenograft (PDX)
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