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Biochemistry

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Quantification of Protein Interaction Network Dynamics using Multiplexed Co-Immunoprecipitation
 

Quantification of Protein Interaction Network Dynamics using Multiplexed Co-Immunoprecipitation

Article doi: 10.3791/60029
August 21st, 2019

Summary August 21st, 2019

Quantitative Multiplex Immunoprecipitation (QMI) uses flow cytometry for sensitive detection of differences in the abundance of targeted protein-protein interactions between two samples. QMI can be performed using a small amount of biomaterial, does not require genetically engineered tags, and can be adapted for any previously defined protein interaction network.

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