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Een methode om de Novo vorming van Chromatin domeinen te bestuderen
JoVE Journal
Genetics
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JoVE Journal Genetics
A Method to Study de novo Formation of Chromatin Domains
DOI:

00:07 min

August 23, 2019

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Chapters

  • 00:04Title
  • 00:37Generation of Clonal EED Knockout Mouse Embryonic Stem Cells
  • 02:51Engineering Cre-ERT2 Based Inducible EED Expression
  • 04:11Following Nucleation and Spreading of PRC2 Activity on Chromatin
  • 05:10Results: Validations and Representative Applications of Inducible EED Rescue Systems
  • 06:43Conclusion

Summary

Automatic Translation

Deze methode is ontworpen om de vorming van PRC2-gemedieerde chromatine-domeinen in cellijnen te volgen, en de methode kan worden aangepast aan vele andere systemen.

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