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Cancer Research

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Isolation and Characterization of Patient-derived Pancreatic Ductal Adenocarcinoma Organoid Models
 

Isolation and Characterization of Patient-derived Pancreatic Ductal Adenocarcinoma Organoid Models

Article doi: 10.3791/60364
January 14th, 2020 Usage Statistics

Summary January 14th, 2020

Patient-derived organoid cultures of pancreatic ductal adenocarcinoma are a rapidly established 3-dimensional model that represent epithelial tumor cell compartments with high fidelity, enabling translational research into this lethal malignancy. Here, we provide detailed methods to establish and propagate organoids as well as to perform relevant biological assays using these models.

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