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Biochemistry

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JoVE Journal Biochemistry
Profilering Ubiquitin og Ubiquitin-lignende avhengige post-translational modifikasjoner og identifisering av vesentlige endringer
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Profilering Ubiquitin og Ubiquitin-lignende avhengige post-translational modifikasjoner og identifisering av vesentlige endringer

Article DOI: 10.3791/60402-v • 10:26 min • November 7th, 2019
November 7th, 2019 •
1, 1, 1, 1, 1, 1, 1, 1
1Aix-Marseille Univ, INSERM, CNRS, Institut Paoli-Calmettes, CRCM

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Summary
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Denne protokollen tar sikte på å etablere ubiquitin (UB) og ubiquitin (Ubls) spesifikke proteomes for å identifisere endringer av disse type post-translational modifikasjoner (PTMs), forbundet med en bestemt tilstand, for eksempel en behandling eller en fenotype.

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Biokjemi post-translational modifikasjoner ubiquitin SUMO Nedd8 proteom profilering endring
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