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JoVE Journal
Chemistry

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Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
 

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Article doi: 10.3791/60442
February 6th, 2020 Usage Statistics

Summary February 6th, 2020

A protocol is presented for the synthesis of information-encoded peptoid oligomers and for the sequence-directed self-assembly of these peptoids into molecular ladders using amines and aldehydes as dynamic covalent reactant pairs and Lewis acidic rare-earth metal triflates as multi-role reagents.

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