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Neuroscience

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Quantitative Measurement of Intrathecally Synthesized Proteins in Mice
 

Quantitative Measurement of Intrathecally Synthesized Proteins in Mice

Article DOI: 10.3791/60495-v
November 29th, 2019

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Summary November 29th, 2019

Elevated spinal fluid protein levels can either be the result of diffusion of plasma protein across an altered blood-brain barrier or intrathecal synthesis. An optimized testing protocol is presented in this article that helps to discriminate both cases and provides quantitative measurements of intrathecally synthesized proteins.

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