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Skivning och odling Gris hjärtan under fysiologiska förhållanden
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Skivning och odling Gris hjärtan under fysiologiska förhållanden

Article DOI: 10.3791/60913-v • 07:54 min • March 20th, 2020
March 20th, 2020 •
*1, *1, 1, 1, 2, 2, 2, 2, 1, 1,3,4,5,6
1Institute of Molecular Cardiology, Department of Medicine, University of Louisville, 2Department of Bioengineering, University of Louisville, 3Diabetes and Obesity Center, Department of Medicine, University of Louisville, 4Department of Pharmacology and Toxicology, University of Louisville, 5Institute of Cardiovascular Sciences, University of Manchester, 6Faculty of Pharmacy, Zagazig University
* These authors contributed equally

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Detta protokoll beskriver hur man skär och kultur hjärtvävnad under fysiologiska förhållanden i 6 dagar. Detta kultursystem skulle kunna användas som en plattform för att testa effekten av nya hjärtsvikt therapeutics samt tillförlitlig testning av akut kardiotoxicitet i en 3D-hjärtmodell.

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Medicin genterapi kardiotoxicitet hjärta elektrisk stimulering kalcium elektrofysiologi biomimetisk kultur farmakologi
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