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Journal / Biology / Mätning ran peptid toxicitet i C. elegans
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Mätning ran peptid toxicitet i C. elegans
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Mätning ran peptid toxicitet i C. elegans

Article DOI: 10.3791/61024-v • 10:49 min • April 30th, 2020
April 30th, 2020 •
1, 2, 2, 1,2
1Graduate Program in Cell Biology and Molecular Physiology, University of Pittsburgh, 2Department of Pediatrics, University of Pittsburgh School of Medicine

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Upprepade-associerade icke-ATG-beroende translationella produkter är nya patogena funktioner i flera upprepa expansion-baserade sjukdomar. Målet med det protokoll som beskrivs är att utvärdera toxicitet orsakad av dessa peptider med hjälp av beteendemässiga och cellulära analyser i modellsystemet C. elegans.

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Biologi Nummer 158 neurodegeneration ALS Huntingtons sjukdom C9orf72 proteotoxicitet upprepade expansionsstörningar
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