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Assessment of Global Ocular Structure Following Spaceflight Using a Micro-Computed Tomography (Micro-CT) Imaging Method
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Assessment of Global Ocular Structure Following Spaceflight Using a Micro-Computed Tomography (Micro-CT) Imaging Method

Article DOI: 10.3791/61227-v • 09:11 min • October 27th, 2020
October 27th, 2020 •
1, 2, 2, 2
1Center for Dental Research, Loma Linda University, 2Department of Basic Sciences, Division of Biomedical Engineering Sciences (BMES), Loma Linda University

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Summary
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We present a protocol using high-resolution micro-computed tomography imaging to determine whether spaceflight induced damage on ocular structures. The protocol shows the micro-CT-derived measurement of ex vivo rodent ocular structures. We demonstrate the ability to assess ocular morphological changes following spaceflight using a non-destructive tridimensional technique to evaluate ocular damage.

Tags

Global Ocular Structure Spaceflight Micro-computed Tomography Imaging Method Physiology Fluid Shifts Intracranial Pressure Spaceflight Associated Neuro-ocular Syndrome (SANS) Optic Disc Edema Globe Flattening Choroidal And Retinal Folds Hyperopic And Refractive Error Shifts Nerve Fiber Layer Infracts Mechanisms Of SANS Rodent Models Non-invasive Imaging Techniques Micro-CT Anatomical Structures Pathological Processes
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