International Space Station

The International Space Station (ISS) is a continuously crewed laboratory in low Earth orbit where researchers study how living systems respond to spaceflight. Its microgravity environment, increased radiation exposure, and altered day-night cycle change forces and conditions that influence cells, microbes, plants, animals, and human physiology, while onboard life-support systems maintain pressure, temperature, air, and water. Biology investigations on the ISS examine processes such as bone loss, muscle decline, immune responses, microbial growth, plant development, and tissue repair using controlled experiments and regular Earth-based comparisons. These results clarify fundamental biology, support astronaut health, and inform medical research and future long-duration missions.

International Space Station - Related Videos

Education

JoVE Science Education - Basic Biology

Emergency Eyewash and Shower Stations

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2023

Robert M. Rioux, Pennsylvania State University, University Park, PA The Occupational Safety and Health Administration (OSHA) mandates that an emergency eyewash and shower station be easily accessible in all workplaces in which a person could be exposed to injurious and/or corrosive substances. Emergency eyewash and shower stations should be used in the case of a laboratory or workplace accident that involves the spilling of a harmful, possibly corrosive chemical onto the body or the splashing...

Research

JoVE Journal - Bioengineering
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In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen

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Cited by 16 •

2012

Simple and reproducible procedures are described for making three structurally distinct collagen assemblies from a common commercially available Type I collagen monomer. Native type, fibrous long spacing or segmental long spacing collagen can be constructed by varying the conditions to which the 300 nm long and 1.4 nm diameter monomer building block is exposed.

Internal Standards

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2023

Source: Laboratory of Dr. B. Jill Venton - University of Virginia The goal of many chemical analyses is a quantitative analysis, where the amount of a substance in a sample is determined. In order to accurately calculate the concentration of an unknown from a sample, careful sample preparation is key. Every time a sample is handled or transferred, some of the sample can be lost. There are strategies however, for minimizing sample loss. There are also strategies for coping with sample loss and...

Education

JoVE Core - Chemistry
Free Sample

Internal Energy

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2020

The total of all possible kinds of energy present in a substance is called the internal energy (U), sometimes symbolized as E. Suppose a system with initial internal energy, Uinitial, undergoes a change in energy (transfer of work or heat), and the final internal energy of the system is Ufinal. Change in internal energy equals the difference between Ufinal and Uinitial. Although the values for Ufinal and Uinitial cannot be determined for a system, the first law of thermodynamics only...

Space Curves

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2026

A space curve describes the path followed by a particle moving through three-dimensional space. Unlike plane curves, which are confined to two coordinates, space curves require three coordinate functions. If t is a parameter, the position of the particle is represented by the vector function\begin{equation*}\mathbf{r}(t)=\langle x(t),y(t),z(t)\rangle,\end{equation*}where x(t), y(t), and z(t) are differentiable functions of t. As t varies over an interval, the endpoints of the position vectors...

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