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JoVE Journal
Cancer Research

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Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
 

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging

Article DOI: 10.3791/61272-v 06:44 min June 7th, 2020
June 7th, 2020

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Summary

Intracranial brain metastasis modeling is complicated by an inability to monitor tumor size and response to treatment with precise and timely methods. The presented methodology couples intracranial tumor injection with magnetic resonance imaging analysis, which when combined, cultivates precise and consistent injections, enhanced animal monitoring, and accurate tumor volume measurements.

Tags

Intracranial Injection Magnetic Resonance Imaging Brain Metastases Tumor Volume Measurement Intercranial Tumor Growth Drill Stereotactic Frame Digital Injector Delivery Rate Anesthetized Mouse Calvarial Window
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