Journal
/
Medicine
/
Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model

Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model

DOI:
10.3791/61546-v

•

07:50 min

•

September 03, 2020

•

, , , ,
1Department of Cardiovascular Medicine,Mayo Clinic, 2Department of Radiology and Molecular Imaging Program at Stanford (MIPS),Stanford University School of Medicine

Chapters

  • 00:04Introduction
  • 00:54Preparation and Intubation
  • 02:10Ischemia Reperfusion Injury
  • 04:15Mouse Mesenchymal Stem Cell Delivery
  • 06:07Results: Heart Function after Ischemic Injury
  • 07:05Conclusion

Summary

Automatic Translation

Automatic Translation

Stems cells are continuously investigated as potential treatments for individuals with myocardial damage, however, their decreased viability and retention within injured tissue can impact their long-term efficacy. In this manuscript we describe an alternative method for stem cell delivery in a murine model of ischemia reperfusion injury.

Tags

AI-assisted WritingStem Cell TherapyIschemia-reperfusion InjuryDelayed Cell DeliverySurgical ProcedureMurine Model

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury

A Murine Closed-chest Model of Myocardial Ischemia and Reperfusion

Ischemia-reperfusion Model of Acute Kidney Injury and Post Injury Fibrosis in Mice

Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion

A Murine Model of Myocardial Ischemia-reperfusion Injury through Ligation of the Left Anterior Descending Artery

Murine Model of Intestinal Ischemia-reperfusion Injury

A Mouse Model of Retinal Ischemia-Reperfusion Injury Through Elevation of Intraocular Pressure

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery

Tracking Superparamagnetic Iron Oxide-labeled Mesenchymal Stem Cells using MRI after Intranasal Delivery in a Traumatic Brain Injury Murine Model

Read Article