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JoVE Journal
Bioengineering

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Controlled Strain of 3D Hydrogels under Live Microscopy Imaging
 

Controlled Strain of 3D Hydrogels under Live Microscopy Imaging

Article DOI: 10.3791/61671-v
December 4th, 2020

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Summary December 4th, 2020

The presented method involves uniaxial stretching of 3D soft hydrogels embedded in silicone rubber while allowing live confocal microscopy. Characterization of the external and internal hydrogel strains as well as fiber alignment are demonstrated. The device and protocol developed can assess the response of cells to various strain regimes.

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