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Gecontroleerde stam van 3D-hydrogels onder live microscopiebeeldvorming
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Gecontroleerde stam van 3D-hydrogels onder live microscopiebeeldvorming

Article DOI: 10.3791/61671-v • 07:41 min • December 4th, 2020
December 4th, 2020 •
1, 2, 3, 3, 2, 3,4
1Department of Biomedical Engineering, Faculty of Engineering, Tel-Aviv University, 2Department of Materials Science and Engineering, Faculty of Engineering, Tel-Aviv University, 3School of Mechanical Engineering, Faculty of Engineering, Tel-Aviv University, 4Center for the Physics and Chemistry of Living Systems, Tel-Aviv University

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De gepresenteerde methode omvat het uniaxiaal uitrekken van 3D zachte hydrogels ingebed in siliconenrubber terwijl live confocale microscopie mogelijk is. Karakterisering van de externe en interne hydrogelstammen en vezeluitlijning worden gedemonstreerd. Het ontwikkelde apparaat en protocol kunnen de reactie van cellen op verschillende stamregimes beoordelen.

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Bioengineering Hydrogel Extracellulaire matrix Mechanobiologie Celmechanica Mechanische kracht Externe stretching Vezelnetwerk Fiber alignment
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