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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Article DOI: 10.3791/61773-v • 08:20 min • March 31st, 2021
March 31st, 2021 •
*1, *1, *2, 2,3, 2, 1
1Department of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University (UNESP), 2Department of Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), 3Faculty of Pharmaceutical Sciences of Ribeiraão Preto (FCFRP-USP), Department of Physics and Chemistry, University of São Paulo
* These authors contributed equally

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Summary
Automatic Translation

Natural products represent promising starting points for the development of new drugs and therapeutic agents. However, due to the high chemical diversity, finding new therapeutic compounds from plants is a challenging and time-consuming task. We describe a simplified approach to identify antimicrobial and antibiofilm molecules from plant extracts and fractions.

Tags

Novel Antimicrobial Molecules Antibiofilm Molecules Plants Extracts Fractions Dental Caries Prevention Systematic Approach Bioactive Candidates Natural Products Screening Oral Biofilms Control Biofilm Research Starch Screening Method Extraction Solvent Ultrasound Assisted Extractions Centrifugation Solid Residue Decapping Chemical Analysis Bioassays Fractionation Process
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