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JoVE Journal
Cancer Research

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Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans
 

Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans

Article DOI: 10.3791/61788-v
October 5th, 2020

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Summary October 5th, 2020

The genetically tractable nematode Caenorhabditis elegans can be used as a simple and inexpensive model for drug discovery. Described here is a protocol to identify anticancer therapeutics that inhibit the downstream signaling of RAS and EGFR proteins.

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