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Cancer Research

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JoVE Journal Cancer Research
Um modelo de xenoenxerto Murine Ommaya para estudar terapia direta da doença leptomeningeal
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Um modelo de xenoenxerto Murine Ommaya para estudar terapia direta da doença leptomeningeal

Article DOI: 10.3791/62033-v • 07:17 min • January 29th, 2021
January 29th, 2021 •
1,2, 3, 4, 4, 1, 5, 6, 7, 4, 2, 1,2
1Department of Neuro-Oncology, H. Lee Moffitt Cancer Center & Research Institute, 2Department of Tumor Biology, H. Lee Moffitt Cancer Center & Research Institute, 3Department of Comparative Medicine, University of South Florida, 4Department of Breast Oncology, H. Lee Moffitt Cancer Center & Research Institute, 5Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, 6Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, 7Department of Medical Oncology, Roswell Park Comprehensive Cancer Center

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Aqui, descrevemos um modelo de xenoenxerto de murina que se assemelha funcionalmente a um reservatório de Ommaya em pacientes. Desenvolvemos a Murine Ommaya para estudar novas terapêuticas para a doença leptomeningeal universalmente fatal.

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Pesquisa do Câncer Questão 167 Doença Leptomeningeal modelos experimentais modelo murino reservatório Murine Ommaya
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