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Biology

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类器官来源的上皮单层:临床相关的肠道屏障功能体外模型
 
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类器官来源的上皮单层:临床相关的肠道屏障功能体外模型

Article DOI: 10.3791/62074-v 09:40 min July 29th, 2021
July 29th, 2021

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Summary

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Click here for the English version.

在这里,我们描述了用于研究肠屏障功能,通透性和运输的人类器官衍生的肠上皮单层的制备。由于类器官代表原始的上皮组织对外部刺激的反应,这些模型结合了细胞系可扩增性的优势以及原代组织的相关性和复杂性。

Tags

生物学,第173期,上皮单层,人类肠道类器官,膜插入,屏障功能,通透性,运输
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