The Preparation of Chicken Ex Ovo Embryos and Chorioallantoic Membrane Vessels as In Vivo Model for Contrast-Enhanced Ultrasound Imaging and Microbubble-Mediated Drug Delivery Studies

7.4K views

Cited by 7

09:53 min

February 9th, 2021

10.3791/62076-v

February 9th, 2021

7.4K views

Bram Meijlink¹ , Ilya Skachkov¹ , Antonius F. W. van der Steen¹^,² , Nico de Jong¹^,² , Klazina Kooiman¹

¹Department of Biomedical Engineering, Thoraxcenter, Erasmus MC University Medical Center Rotterdam, ²Laboratory of Acoustical Wavefield Imaging, Faculty of Applied Sciences, Delft University of Technology

This protocol describes three methods on how to obtain and use 5 to 8-day old chicken embryos and their chorioallantoic membrane (CAM) as an in vivo model to study contrast-enhanced ultrasound imaging and microbubble-mediated drug delivery.

Explore More Videos

Chicken Embryo Model

Microbubble Drug Delivery

CAM Vessels

Ex Ovo Preparation

Ultrasound Contrast Agents

Vascular Imaging

Embryo Injection

Chapters in this video