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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Article DOI: 10.3791/62230-v • 09:02 min • February 2nd, 2021
February 2nd, 2021 •
1, 1, 1, 1, 1, 1, 1
1Department of Cardiac Surgery, Boston Children’s Hospital, Harvard Medical School

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This study presents a highly reproducible large animal model of renal ischemia-reperfusion injury in swine using temporary percutaneous bilateral balloon-catheter occlusion of the renal arteries for 60 min and reperfusion for 24 h.

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Large Animal Model Acute Kidney Injury Renal Artery Occlusion Pathophysiology Therapeutic Modalities Reproducible Inflammatory Response Preclinical Model Renal Transplantation Renal Hypoperfusion Transcatheter Procedures Cardiovascular Procedures Disinfect Betadine Ethanol Cutdown Catheterization Carotid Artery Jugular Vein Sternocleidomastoid Muscle Angiography Sheath Seldinger Technique Femoral Artery
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