Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Neuroscience / Multiplexed Analysis of Retinal Gene Expression…
JoVE Journal
Neuroscience

A subscription to JoVE is required to view this content.

JoVE Journal Neuroscience
Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq
Transcriptome Analysis of Single Cells
Journal (Neuroscience)
Transcriptome Analysis of Single Cells
Simultaneous Recording of Calcium Signals from Identified Neurons and Feeding Behavior of Drosophila melanogaster
Journal (Neuroscience)
Simultaneous Recording of Calcium Signals from Identified Neurons and Feeding Behavior of Drosophila melanogaster
 

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

Article DOI: 10.3791/62239-v • 06:24 min • March 12th, 2021
March 12th, 2021 •
*1, *1, 1, 1,2,3,4,5,6
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine
* These authors contributed equally

Chapters

Summary
Automatic Translation

Here, the authors showcase the utility of MULTI-seq for phenotyping and subsequent paired scRNA-seq and scATAC-seq in characterizing the transcriptomic and chromatin accessibility profiles in retina.

Tags

Single-cell RNA-seq ScRNA-Seq Single-cell ATAC-seq ScATAC-Seq MULTI-seq Gene Regulatory Networks Development Disease Progression Anchor Barcode Solution Co-anchor Solution 1% BSA And PBS Gel Bead-in-Emulsion (GEM)
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter